CIRCULAR RNA CIRCERBB2 PROMOTES GALLBLADDER CANCER PROGRESSION BY REGULATING PA2G4-DEPENDENT RDNA TRANSCRIPTION

Circular RNA circERBB2 promotes gallbladder cancer progression by regulating PA2G4-dependent rDNA transcription

Abstract Background CircRNAs are found to affect initiation and progression of several cancer types.However, whether circRNAs are implicated in gallbladder cancer (GBC) progression remains obscure.Methods We perform RNA sequencing in 10 pairs of GBC and para-cancer tissues.CCK8 and clone formation assays are used to evaluate proliferation ability L

read more

Mathematical modeling of dispersed media flows in the presence of nucleation, coagulation and phase transitions

A model of motion of a gas-dispersed medium in the presence of processes of nucleation, coagulation and phase transitions has been constructed.A homogeneous Teacup and Saucer nucleation model is used to describe the nucleation process.It is believed that the process of cluster coagulation occurs due to their Brownian motion.The analysis of the solu

read more

Control the Epithelial Barrier: A Pivotal First Line of Defense

Lumen-derived material gains access to the mucosa by permeating between adjacent epithelial 6-Piece Dining Set cells (ie, paracellular pathway), by transcytosis across the apical and basolateral cell membranes (ie, transcellular pathway) or by exploiting breaks or erosions in the epithelium that may, for example, result from inflammation.Increased

read more

In Silico Evaluation of a Mutant Toxic Shock Syndrome Toxin-1 (TSST-1) of Staphylococcus aureus as a Putative Vaccine Candidate

Introduction: The development of a vaccine against Staphylococcus aureus has proven to be much more difficult than expected.In this study, we considered and analyzed a mutant Toxic Shock Syndrome Toxin-1 (TSST-1) as a potential vaccine candidate.Methods: An SHAMPOO CITRUS NCBI sequence of TSST-1 was analyzed bioinformatically by online tools such a

read more